We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Genetic polymorphism of 38 Y-chromosome short tandem repeats in Beijing han population from China.
- Authors
Liu, Yan; Jiang, Chengtao; Zhao, Dong; Zhang, Jinpei; Wu, Libin; Lu, Di; Yuan, Li
- Abstract
Objective: To investigate 38 Y-chromosome short tandem repeat (Y-STR) genetic polymorphisms in Beijing Han and analyze the genetic distance with neighboring or linguistically similar populations. Materials and Methods: In the study, we selected 531 unrelated male individuals of Beijing Han, and the results were statistically analyzed by testing with GSTAR™ 41Y reagents. Results: The allele peak heights were balanced among the Y loci, the amplified fragment ranged from 100 to 500 bps. A total of 531 haplotypes were detected in 531 samples. Eight null genotypes were observed on locus DYS448. One and three double alleles were observed on single-copy locus DYS576 and DYS19, respectively. DYS385 a/b, DYF387S1 a/b, and DYS527 a/b were more common in double copies, but 3, 13, and 11 triple alleles were detected, respectively. The gene diversity values of Y-STRs except DYS391, DYS438, and DYS645 were >0.5. Twenty-seven Y-STRs of Beijing Han population were selected for genetic distance comparison with 17 populations including Changchun Han, with Rst values ranging from 0.0002 to 0.1703. Conclusion: The 38 Y-STRs in this study have strong male lineage identification ability and have great potential for individual identification, kinship identification, Y-STR database construction, and genetic relationship research.
- Subjects
BEIJING (China); SHORT tandem repeat analysis; Y chromosome; GENETIC polymorphisms; KINSHIP; LINEAGE
- Publication
Journal of Forensic Science & Medicine, 2023, Vol 9, Issue 4, p340
- ISSN
2349-5014
- Publication type
Article
- DOI
10.4103/jfsm.jfsm_105_23