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- Title
Follicular-fluid anti-Müllerian hormone concentration is similar in patients with endometriosis compared with non-endometriotic patients.
- Authors
Campos, C. S.; Vaamonde, D.; Andreoli, C.; Martins, A. C.; Genro, V. K.; Souza, C. A.; Chapon, R.; Cunha-Filho, J. S. L.
- Abstract
This cross-sectional prospective study assessed follicular-fluid anti-Müllerian hormone (AMH) concentrations in infertile patients with mild/minimal endometriosis during natural IVF. Thirty-two women participated in the study. Patients were divided into two groups: tubal obstruction without endometriosis (control group) and minimal/mild endometriosis (study group). All patients underwent laparoscopy for assessment of infertility; at the same time, any foci of endometriosis found were cauterized. AMH concentration was measured in the follicular fluid of a single follicle when it achieved pre-ovulatory maturation by ultrasensitive enzyme-linked immunosorbent assay. Likewise, AMH, FSH and inhibin B content in serum was also measured. Age (30 ± 1.3 and 32 ± 0.8 years) and body mass index (22 ± 0.6 and 22 ± 0.5 kg/m²), day-3 antral follicle count (11.3 ± 1.7 and 10.7 ± 1.5), serum FSH concentrations (5.4 ± 0.6 and 5.0 ± 0.3 IU/ml) and follicular-fluid AMH concentrations (1.8 ± 0.3 and 1.5 ± 0.1 ng/ml, study and control group, respectively; mean difference 0.33, 95% CI -0.21 to 0.88) were similar in both groups. This study shows that infertile patients with minimal/mild endometriosis have a similar concentration of AMH in the follicular fluid after natural IVF as compared with control subjects.
- Subjects
ENDOMETRIOSIS; HORMONES; CONTROL groups; SERUM; BODY mass index; FERTILIZATION in vitro
- Publication
Reproductive BioMedicine Online (Reproductive Healthcare Limited), 2010, Vol 21, Issue 4, p470
- ISSN
1472-6483
- Publication type
Article
- DOI
10.1016/j.rbmo.2010.05.007