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Mutant Exon1 Huntingtin Aggregation is Regulated by T3 Phosphorylation-Induced Structural Changes and Crosstalk between T3 Phosphorylation and Acetylation at K6.
Published in:
Angewandte Chemie, 2017, v. 129, n. 19, p. 5286, doi. 10.1002/ange.201611750
By:
- Chiki, Anass;
- DeGuire, Sean M.;
- Ruggeri, Francesco S.;
- Sanfelice, Domenico;
- Ansaloni, Annalisa;
- Wang, Zhe‐Ming;
- Cendrowska, Urszula;
- Burai, Ritwik;
- Vieweg, Sophie;
- Pastore, Annalisa;
- Dietler, Giovanni;
- Lashuel, Hilal A.
Publication type:
Article
Frontispiz: Mutant Exon1 Huntingtin Aggregation is Regulated by T3 Phosphorylation-Induced Structural Changes and Crosstalk between T3 Phosphorylation and Acetylation at K6.
Published in:
Angewandte Chemie, 2017, v. 129, n. 19, p. n/a, doi. 10.1002/ange.201781961
By:
- Chiki, Anass;
- DeGuire, Sean M.;
- Ruggeri, Francesco S.;
- Sanfelice, Domenico;
- Ansaloni, Annalisa;
- Wang, Zhe‐Ming;
- Cendrowska, Urszula;
- Burai, Ritwik;
- Vieweg, Sophie;
- Pastore, Annalisa;
- Dietler, Giovanni;
- Lashuel, Hilal A.
Publication type:
Article
Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-97334-z
By:
- Herrmann, Frank;
- Hessmann, Manuela;
- Schaertl, Sabine;
- Berg-Rosseburg, Karola;
- Brown, Christopher J;
- Bursow, Galina;
- Chiki, Anass;
- Ebneth, Andreas;
- Gehrmann, Miriam;
- Hoeschen, Nicole;
- Hotze, Madlen;
- Jahn, Stefanie;
- Johnson, Peter D;
- Khetarpal, Vinod;
- Kiselyov, Alex;
- Kottig, Karsten;
- Ladewig, Stefanie;
- Lashuel, Hilal;
- Letschert, Sven;
- Mills, Matthew R
Publication type:
Article
Mutant Exon1 Huntingtin Aggregation is Regulated by T3 Phosphorylation-Induced Structural Changes and Crosstalk between T3 Phosphorylation and Acetylation at K6.
Published in:
Angewandte Chemie International Edition, 2017, v. 56, n. 19, p. 5202, doi. 10.1002/anie.201611750
By:
- Chiki, Anass;
- DeGuire, Sean M.;
- Ruggeri, Francesco S.;
- Sanfelice, Domenico;
- Ansaloni, Annalisa;
- Wang, Zhe-Ming;
- Cendrowska, Urszula;
- Burai, Ritwik;
- Vieweg, Sophie;
- Pastore, Annalisa;
- Dietler, Giovanni;
- Lashuel, Hilal A.
Publication type:
Article
Frontispiece: Mutant Exon1 Huntingtin Aggregation is Regulated by T3 Phosphorylation-Induced Structural Changes and Crosstalk between T3 Phosphorylation and Acetylation at K6.
Published in:
Angewandte Chemie International Edition, 2017, v. 56, n. 19, p. n/a, doi. 10.1002/anie.201781961
By:
- Chiki, Anass;
- DeGuire, Sean M.;
- Ruggeri, Francesco S.;
- Sanfelice, Domenico;
- Ansaloni, Annalisa;
- Wang, Zhe-Ming;
- Cendrowska, Urszula;
- Burai, Ritwik;
- Vieweg, Sophie;
- Pastore, Annalisa;
- Dietler, Giovanni;
- Lashuel, Hilal A.
Publication type:
Article
TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models.
Published in:
EMBO Journal, 2020, v. 39, n. 17, p. 1, doi. 10.15252/embj.2020104671
By:
- Hegde, Ramanath Narayana;
- Chiki, Anass;
- Petricca, Lara;
- Martufi, Paola;
- Arbez, Nicolas;
- Mouchiroud, Laurent;
- Auwerx, Johan;
- Landles, Christian;
- Bates, Gillian P;
- Singh‐Bains, Malvindar K;
- Dragunow, Mike;
- Curtis, Maurice A;
- Faull, Richard LM;
- Ross, Christopher A;
- Caricasole, Andrea;
- Lashuel, Hilal A
Publication type:
Article
Site‐Specific Phosphorylation of Huntingtin Exon 1 Recombinant Proteins Enabled by the Discovery of Novel Kinases.
Published in:
ChemBioChem, 2021, v. 22, n. 1, p. 217, doi. 10.1002/cbic.202000508
By:
- Chiki, Anass;
- Ricci, Jonathan;
- Hegde, Ramanath;
- Abriata, Luciano A.;
- Reif, Andreas;
- Boudeffa, Driss;
- Lashuel, Hilal A.
Publication type:
Article
Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity.
Published in:
NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00388-7
By:
- Lashuel, Hilal A.;
- Mahul-Mellier, Anne-Laure;
- Novello, Salvatore;
- Hegde, Ramanath Narayana;
- Jasiqi, Yllza;
- Altay, Melek Firat;
- Donzelli, Sonia;
- DeGuire, Sean M.;
- Burai, Ritwik;
- Magalhães, Pedro;
- Chiki, Anass;
- Ricci, Jonathan;
- Boussouf, Manel;
- Sadek, Ahmed;
- Stoops, Erik;
- Iseli, Christian;
- Guex, Nicolas
Publication type:
Article
A simple, versatile and robust centrifugation‐based filtration protocol for the isolation and quantification of α‐synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α‐synuclein research
Published in:
Journal of Neurochemistry, 2020, v. 153, n. 1, p. 103, doi. 10.1111/jnc.14955
By:
- Kumar, Senthil T.;
- Donzelli, Sonia;
- Chiki, Anass;
- Syed, Muhammed Muazzam Kamil;
- Lashuel, Hilal A.
Publication type:
Article
Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16564-3
By:
- Stephens, Amberley D.;
- Zacharopoulou, Maria;
- Moons, Rani;
- Fusco, Giuliana;
- Seetaloo, Neeleema;
- Chiki, Anass;
- Woodhams, Philippa J.;
- Mela, Ioanna;
- Lashuel, Hilal A.;
- Phillips, Jonathan J.;
- De Simone, Alfonso;
- Sobott, Frank;
- Schierle, Gabriele S. Kaminski
Publication type:
Article
Exploring the role of post‐translational modifications in regulating α‐synuclein interactions by studying the effects of phosphorylation on nanobody binding.
Published in:
Protein Science: A Publication of the Protein Society, 2018, v. 27, n. 7, p. 1262, doi. 10.1002/pro.3412
By:
- El Turk, Farah;
- De Genst, Erwin;
- Guilliams, Tim;
- Fauvet, Bruno;
- Hejjaoui, Mirva;
- Di Trani, Justin;
- Chiki, Anass;
- Mittermaier, Anthony;
- Vendruscolo, Michele;
- Lashuel, Hilal A.;
- Dobson, Christopher M.
Publication type:
Article

Found: 11