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- Title
Anti-Inflammatory and Analgesic Activities of Oxadiazoles Combined with the Nucleus of Benzothiazole.
- Authors
KUMAR, VISHAL; SHARMA, SATISH KUMAR; AHMAD, RIZWAN
- Abstract
The study aims to synthesise and assess the anti-inflammatory and analgesic potency of derivatives from 2, 3, 3-benzathiazole. The present study has synthesised a number of derivatives for phosphorus oxychloride condensation (Benzothiazolyl Carboxyhydrazides and Aryl derivatives) namely two (5-substitutes-1,3,4-oxadiazol 2-yl). Benzothiazol (vt1-vt9). Synthesized IR, 1H NMR and mass spectroscopy compound structures have been established. Checking of all synthesised materials was performed at 50 mg/kg and 10 mg/kg p.o. Anti-inflammatory and analgesic function for in-vivo. There were also positive anti-inflammatory and analgesic results of some drugs.
- Subjects
ANTI-inflammatory agents; OXADIAZOLES; BENZOTHIAZOLE; MASS spectrometry; NUCLEAR magnetic resonance spectroscopy
- Publication
International Journal of Pharmaceutical Research (09752366), 2021, Vol 13, Issue 1, p2003
- ISSN
0975-2366
- Publication type
Article
- DOI
10.31838/ijpr/2021.13.01.390