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- Title
Association between Abnormal Yolk Sac and Spontaneous Miscarriage: A Cohort Study.
- Authors
Geddoa, Salam; aljassany, Fatima; Jasim, AbdulRazzaq Oleiwi
- Abstract
Background: The yolk sac is essential in early life of the embryo because it is the first route of exchange between the embryo and the mother. Aim of the study: To determine the association of the spontaneous miscarriage with the abnormal morphology and size of the yolk sac. Methods: A cohort study was conducted among 85 pregnant women with gestational age ranged between 7-12 weeks, transvaginal ultrasonography was done for all patients at first time. The gestational age was calculated according to the last menstrual period (LMP), crown-rump lengths (CRL), mean gestational sac diameters (MGSD). We divided the sample into two groups, 27 women had abnormal yolk sac represented the 1st group (study) and 53 women had normal sonographic appearance of the yolk sac represented the 2nd group (control). We followed the women until the 20th weeks of pregnancy and compared the spontaneous miscarriage rate between the two groups. Results: Most of the embryos had a yolk sac with a regular shape (80%), whereas the remaining embryos had a yolk sac with an irregular shape (15%), calcified 2.5%. and 2.5% echogenic. about one third of the women with abnormal yolk sac (cohort group) had miscarriage in front of 10.9% of the control group and the association was significant (p value = 0.013). Significant association between spontaneous miscarriage and abnormal large diameter yolk sac. Conclusion: Abnormal yolk sac increases significantly the risk of spontaneous miscarriage.
- Subjects
YOLK sac; MISCARRIAGE; TRANSVAGINAL ultrasonography; GESTATIONAL age; COHORT analysis
- Publication
Kerbala Jorunal of Medicine, 2020, Vol 13, Issue 1, p2282
- ISSN
1990-5483
- Publication type
Article