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- Title
P-112: Myocardial and vascular remodeling and biochemical markers of vascular dysfunction in refractory hypertensives.
- Authors
Cittadino, Maira; Sousa, Marcio G.; Yugar-Toledo, Juan C.; Rocha, Joao C.; Tanus-Santos, Jose E.; Moreno, Heitor
- Abstract
In this study, left ventricular mass index (LVMI), ejection fraction (EF), carotid thickness (based on ultrasound) and plasma nitric oxide (NO2/NO3), cGMP, and thromboxane B2 levels were evaluated in refractory hypertensives (RH, n=11) and healthy volunteers (Control, n=11). The LVMI was higher in the RH group (138.3 ± 19.8 vs 108.3 ± 17.3), but there was no significant difference in EF between the two groups. Carotid thickness was significantly higher in RH patients (1.6±0.2 vs 1.0±0.1; p<0.001), whereas the plasma NO2/NO3, cGMP and thromboxane B2 concentrations were similar (Table; mean±SEM).These results show that there was no correlation between the biochemical markers assessed and myocardial/vascular remodeling in refractory hypertensive patients.Am J Hypertens (2001) 14, 67A-67A; doi:S0895-7061(01)01663-6
- Publication
American Journal of Hypertension, 2001, Vol 14, p67A
- ISSN
0895-7061
- Publication type
Article
- DOI
10.1016/S0895-7061(01)01663-6