We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
HIPERPLASIA CONGÊNITA DE SUPRARRENAL NO TESTE DO PEZINHO.
- Authors
SILVA, PAULA; SOUZA GUEDES, LUIZ FELIPE; VALADÃO, ANALINA FURTADO; DA MOTTA, PATRÍCIA GONÇALVES; SOARES, JAQUELINE MELO
- Abstract
Neonatal screening of Congenital Adrenal Hyperplasia (CAH) decreases serious medical and social complications for patients, as acute exacerbations of salt loss and even incorrect civil records of female children. It contributes significantly to the reduction of the interval between diagnosis and early treatment of children affected by the disease, reducing the morbidity and mortality. The CAH deficiency of D21-OH enzyme is considered eligible for inclusion in newborn screening programs. The disease is relatively common, potentially fatal in infancy and easily screened. The aim of this study was to evaluate the number of positive and false positive cases in the CAH pilot project for congenital adrenal hyperplasia, from Newborn Screening Program conducted at clinics in Ipatinga. From September 2007 to April 2008, Ipatinga recorded 2108 live births. Of this total, ten (0.47%) exceeded the 17-OHP cutoff values established in the first sample on filter paper, and three of them were female. After screened, patients were clinically followed for prognosis and progression. The ten patients with positive initial screening for CAH did not show, clinical or laboratory manifestations of the disease under study. Regardless of the outcome, the implementation of any method of screening for CAH is valid because it saves lives and enables monitoring with appropriate therapeutic support the needs of each patient.
- Publication
Brazilian Journal of Surgery & Clinical Research, 2014, Vol 8, Issue 2, p7
- ISSN
2317-4404
- Publication type
Article