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- Title
Evidence profesionálních expozic genotoxickým faktorům v Moravskoslezském kraji.
- Authors
Závacká, I.; Ambroz, P.; Janout, V.; Lehocká, H.
- Abstract
The objective of the work was to describe and analyze data kept in the files of the registry of occupational exposure to genotoxic factors within the Moravia-Silesia region. We selected 748 persons whose data were kept in the registry since 2005 for at least three years, mostly in the exposure to genotoxic factors of chemical nature. The mean duration of exposure was 15.1 years. Cytogenetic analysis of human peripheral lymphocytes was performed 492 subjects out of the 748 individuals. The group of increased and high exposure to genotoxic factors included 341 persons. The results indicate an increase exposure to genotoxic factors and thereby increased probability in development of tumor diseases. The persons whose values of percentage of aberrant cells had been repeatedly elevated were subsequently laid off the exposure and often also excluded from the register. Moreover, persons who died or were laid off the job were also excluded from the register. In this way, regular follow up was disrupted at the time, when there is the highest possibility that the biological effect of long-term exposure to genotoxic substances becomes manifest due to latency period the provision of preventive care was also disrupted.
- Publication
Occupational Medicine / Pracovní Lékarství, 2012, Vol 64, Issue 2/3, p86
- ISSN
0032-6291
- Publication type
Article