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- Title
Hepatitis E Infection in HIV-Infected Patients.
- Authors
Rivero-Juarez, Antonio; Lopez-Lopez, Pedro; Frias, Mario; Rivero, Antonio
- Abstract
Background: The hepatitis E virus (HEV) represents a major cause of acute hepatitis worldwide. The majority of HEV cases occur in low-income countries, mainly Asia and Africa, where HEV causes large outbreaks associated with the consumption of contaminated water and high mortality in specific populations. In high-income countries, HEV infection is considered a zoonotic disease that is linked to the consumption of contaminated food. Although a high proportion of cases have self-limiting asymptomatic or subclinical infections, immunosuppression may modify the pathogenesis and clinical impact of this emerging disease. Results and Discussion: Here, we review the current knowledge about the epidemiology, diagnosis, clinical manifestations, management and prevention of HEV infection in HIV-infected subjects. Conclusions: Despite the increasing knowledge about the pathogenesis, epidemiology and clinical impact of HEV infection, several major factors are faced by HIV-infected patients, including treatment recommendations, immunization and risk practices.
- Subjects
ASIA; AFRICA; HEPATITIS E virus; HEPATITIS E; FOOD contamination; THERAPEUTICS; ZOONOSES; WATER pollution
- Publication
Frontiers in Microbiology, 2019, pN.PAG
- ISSN
1664-302X
- Publication type
Article
- DOI
10.3389/fmicb.2019.01425