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- Title
An Instructive Case of Cerebral Mucormycosis .
- Authors
Shao, Belinda; Hagan, Matthew J.; Sastry, Rahul A.; Kritselis, Michael; Donahue, John E.; Toms, Steven A.
- Abstract
Background: Mucormycosis can lead to fatal rhinocerebral infection. Case: A 53-year-old male with diabetes presented with altered mental status. He had been recently discharged from an admission for COVID-19 pneumonia treated with remdesivir and methylprednisolone. Imaging demonstrated a large left frontal mass with midline shift suspicious for a primary brain neoplasm. His neurologic exam rapidly declined and the patient was taken to the operating room for decompressive hemicraniectomy. Post-operatively, the patient remained comatose and failed to improve. Autopsy revealed a cerebral mucormycosis infection. Discussion: Despite concern for a primary brain neoplasm the patient was diagnosed postmortem with a mucormycosis infection. Other features supporting this diagnosis included nasal sinusitis on initial scans, his fulminant clinical decline, rapidly progressive imaging findings, and persistent hyperglycemia throughout his clinical course. Conclusion: In an era of high steroid usage to treat COVID-19, mucormycosis infection must be considered in high-risk patients demonstrating disproportionate clinical decline.
- Subjects
MUCORMYCOSIS; BRAIN tumors; CEREBRAL infarction; OPERATING rooms; DIABETIC acidosis; HYPERGLYCEMIA
- Publication
Rhode Island Medical Journal, 2022, Vol 105, Issue 2, p8
- ISSN
0363-7913
- Publication type
Article