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- Title
Correction to: An Integral Pharmacokinetic Analysis of Piperacillin and Tazobactam in Plasma and Urine in Critically Ill Patients.
- Authors
Wallenburg, Eveline; ter Heine, Rob; Schouten, Jeroen A.; Raaijmakers, Jelmer; ten Oever, Jaap; Kolwijck, Eva; Burger, David M.; Pickkers, Peter; Frenzel, Tim; Brüggemann, Roger J. M.
- Abstract
Based on the correct simulations a dose of 20 g/24 h is inadequate to reach a target of 100% I f i T SB >5×MIC sb for patients with creatinine clearances of 10-60 mL/min. The blue horizontal lines represents a target of 100% fT>1xMIC (22.9 mg/L) and 100% fT>5xMIC (114 mg/L), assuming an MIC of 16 mg/L. The red horizontal line represents the upper limit of toxicity (157 mg/L).
- Subjects
PIPERACILLIN; CRITICALLY ill; TAZOBACTAM; PHARMACOKINETICS; URINE; CEFTAZIDIME
- Publication
Clinical Pharmacokinetics, 2022, Vol 61, Issue 9, p1325
- ISSN
0312-5963
- Publication type
Article
- DOI
10.1007/s40262-022-01165-8