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- Title
Çeşitli klinik örneklerden izole edilen Stenotrophomonas maltophilia suşlarında antibiyotiklere direnç oranı.
- Authors
Şen, Pınar; Yula, Erkan; Er, Hakan; Güngör, Serdar; Özdemir, Rahim; Baran, Nurten; Demirdal, Tuna; Demirci, Mustafa
- Abstract
Aim: Stenotrophomonas maltophilia (S.maltophilia) is a multi-drug resistant non-fermentative gram negative bacilli that causes opportunistic infections especially in hospitalized patients. S.maltophilia strains show a high level of resistance to routinely tested antibiotics such as penicillins, cephalosporins, aminoglycosides, quinolones and carbapenems therefore the treatment of this strains is quite difficult. The aim of this study to determine the resistance patterns of S.maltophilia strains isolated from various clinical specimens during a six year period. Material and Method: The antimicrobial resistance patterns and distribution of 202 S.maltophilia strains isolated from services and outpatients during a period of six years (2010-2015) were analyzed retrospectively. Identification and antimicrobial susceptibilities of the isolates were determined by conventional methods and BD Phoenix 100 (Becton-Dickinson, USA) automated systems. Antibiotic susceptibilities were established by disk diffusion and were evaluated according to the CLSI criteria in 2011-2014 and EUCAST criteria in 2015. Results: A total of 202 strains were isolated from services (62.4%), intensive care units (28.7%) and outpatient clinics (8.9%). 122 patients (60.4%) were male and 80 (39.6%) of them were female. Respiratory tract specimens (n=69) were the most common specimens that S. maltophilia strains were isolated. These strains were found most resistant to meropenem (92.8%) and most sensitive to trimethoprim-sulfamethoxazole (1%). Conclusion: Our resistance rates in S.maltophilia strains were found lower for trimethoprim-sulfamethoxazole, relatively higher for levofloxacin and ciprofloxacin and similar to the other antibiotics compared with the rate in our country. Antimicrobial resistance rates of S.maltophilia strains vary among centers. We believe that it is important to determine their resistance rate of each center for deciding emprical antibiotherapy.
- Publication
Ortadogu Medical Journal / Ortadogu Tip Dergisi, 2017, Vol 9, Issue 3, p113
- ISSN
1309-3630
- Publication type
Article
- DOI
10.21601/ortadogutipdergisi.265431