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- Title
Single dose methotrexate in treatment of ectopic pregnancy: review of 32 case.
- Authors
Aybatli, Aysun; Kaplan, Petek Balkanli; Alicik, Mehmet; Sayin, Niyazi Cenk; Yuce, Mehmet Ali
- Abstract
Objective: To evaluate the efficacy of single dose intramuscular methotrexate in the treatment of ectopic pregnancy. Material and Methods: 32 patients who matched the inclusion criteria were enrolled. Success of treatment was defined as a resolution of ectopic pregnancy without performing surgical intervention. The cases in whom the treatment was successful and those that were not were compared for ß-hCG values and clinical features. Results: ß-hCG at diagnosis averaged 1293.9 mIU/ml. Of the 32 patients who received methotrexate, 26 were successfully treated. 23 patients (71.8%) received a single dose of methotrexate, 3 patients (9.3%) received an additional dose of methotrexate, 6 patients (18.7%) who had failed methotrexate required surgery for cure. The success rate of single-dose methotrexate was 79.3%. Conclusion: Our study shows that single dose systemic methotrexate treatment can be used as an option in unruptured pregnancies.
- Publication
Balkan Medical Journal, 2011, Vol 28, Issue 1, p10
- ISSN
2146-3123
- Publication type
Journal Article