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- Title
Bacteriophage Assembly.
- Authors
Aksyuk, Anastasia A.; Rossmann, Michael G.
- Abstract
Bacteriophages have been a model system to study assembly processes for over half a century. Formation of infectious phage particles involves specific protein-protein and protein-nucleic acid interactions, as well as large conformational changes of assembly precursors. The sequence and molecular mechanisms of phage assembly have been elucidated by a variety of methods. Differences and similarities of assembly processes in several different groups of bacteriophages are discussed in this review. The general principles of phage assembly are applicable to many macromolecular complexes.
- Subjects
BACTERIOPHAGES; PROTEIN-protein interactions; ORGANELLE formation; MACROMOLECULES; GENOMES
- Publication
Viruses (1999-4915), 2011, Vol 3, Issue 3, p172
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v3030172