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- Title
Enzyme from Padina arborescens Holmes Synthesizes Parinaric Acid, a Conjugated Tetraenoic Fatty Acid, from α-Linolenic Acid.
- Authors
Hisaaki Ito; Taro Honma; Hidetsugu Tabata; Tomoyuki Koyama; Shigeaki Ueno; Kayoko Kita; Toshihide Suzuki
- Abstract
Conjugated fatty acids have anticancer effects. Therefore, the establishment of a synthetic method for conjugated fatty acids is important for overcoming cancer. Here, we attempted to synthesize conjugated fatty acids using enzymes extracted from seaweeds containing these fatty acids. Lipids from 12 species of seaweeds from the seas around Japan were analyzed, and Padina arborescens Holmes was found to contain conjugated fatty acids. Then, we synthesized parinaric acid, a conjugated tetraenoic acid, from α-linolenic acid using the enzyme of P. arborescens. This method is expected to have a variety of potential applications for overcoming cancer.
- Subjects
JAPAN; ENZYMES; ACIDS; LINOLEIC acid; ANTINEOPLASTIC agents; MARINE algae
- Publication
Journal of Oleo Science, 2024, Vol 73, Issue 5, p743
- ISSN
1345-8957
- Publication type
Article
- DOI
10.5650/jos.ess23209