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- Title
Regulation of a restriction and modification system via DNA inversion in Mycoplasma pulmonis.
- Authors
Dybvig, Kevin; Yu, Huilan
- Abstract
An invertible DNA element of 6.8 kb, designated the <em>hsd1</em> locus, was identified in the chromosome of <em>Mycoplasma pulmonis</em>. Infection of host cells with mycoplasma virus P1 revealed that the organism's restriction and modification (R-M) properties are controlled by inversion of <em>hsd1</em>. The nucleotide sequence of <em>hsd1</em> revealed several genes, the predicted amino acids of which bear striking similarity to the subunits of the type I R-M enzymes previously found only in enteric bacteria.
- Subjects
DNA; CHROMOSOMES; MYCOPLASMA; NUCLEOTIDE sequence; GENES; ENZYMES
- Publication
Molecular Microbiology, 1994, Vol 12, Issue 4, p547
- ISSN
0950-382X
- Publication type
Article
- DOI
10.1111/j.1365-2958.1994.tb01041.x