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- Title
Numerical evaluation of the effectiveness of coronary revascularization.
- Authors
Simakov, Sergey S.; Gamilov, Timur M.; Liang, Fuyou; Gognieva, Daria G.; Gappoeva, Mariam K.; Kopylov, Philipp Yu.
- Abstract
In the present paper we construct the model of coronary flow which utilizes the patient's CT data on both large CA and perfusion. We reconstruct large coronary vessels based on the CT data and extrude possibly invisible vessels from the branches of the left coronary artery so that every terminal point supply every of standardized zone of myocardium. We apply a previously developed and validated 1D model of haemodynamics. Utilizing the patient-specific CTP data for modifying outflow terminal resistance at rest and under stress conditions is the major novelty of the present work. From our results it follows that acceptable values of fractional flow reserve (FFR) after the stenotic treatment may produce false negative output. Therefore healthy FFR values may be observed after ineffective revascularization. We also conclude that microvascular perfusion impairment plays significant role in correct computational estimation of haemodynamic indices before stenotic treatment. The advantage of the presented approach is the availability of transmural perfusion ratio assessment in everyday practice.
- Subjects
CORONARY arteries; CORONARY circulation; HEMODYNAMICS; PERFUSION
- Publication
Russian Journal of Numerical Analysis & Mathematical Modelling, 2021, Vol 36, Issue 5, p303
- ISSN
0927-6467
- Publication type
Article
- DOI
10.1515/rnam-2021-0025