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- Title
Overcoming resistance to osimertinib in non-small cell lung cancer: Hopes, doubts, and in-between.
- Authors
Passaro, Antonio; Malapelle, Umberto; Attili, Ilaria; Marinis, Filippo; de Marinis, Filippo
- Abstract
The identification of resistance mechanisms to third‐generation tyrosine kinase inhibitors—in particular osimertinib—should be considered as a cornerstone for understanding treatment individualization in an era of precision medicine, potentially improving patient outcomes significantly through a multifactorial strategy.
- Subjects
NON-small-cell lung carcinoma; PROTEIN-tyrosine kinases; INDIVIDUALIZED medicine; KINASE inhibitors; ACRYLAMIDE; AMINES; CELL receptors; LUNG cancer; LUNG tumors; GENETIC mutation; GENOMICS; PROTEIN kinase inhibitors
- Publication
Cancer (0008543X), 2020, Vol 126, Issue 11, p2594
- ISSN
0008-543X
- Publication type
editorial
- DOI
10.1002/cncr.32810