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- Title
Hospital-acquired intestinal toxemia botulism in a newly diagnosed adult colon cancer patient.
- Authors
Lucas José Sá da Fonseca; Diogo Couto de Carvalho; Helena Providelli de Moraes; Izabela Dayany França Feitosa; Gil Pereira Neto; Rodrigo Vasconcellos Vilela; Breno Franco Silveira Fernandes; Rodrigo Santiago Gomez; Nobre, Vandack
- Abstract
This manuscript reports a case of intestinal toxemia botulism in an adult with recently diagnosed metastatic colon cancer in whom botulism symptoms began 23 days after hospital admission. Representing the rarest form of botulism presentation in clinical practice, this infectious disease may have developed due to a cluster of predisposing factors that favored Clostridium botulinum colonization and the endogenous production of neurotoxins, among which are previous use of broad-spectrum antibiotics and colon changes related to the development of the neoplasia. This case highlights the importance of considering intestinal toxemia botulism in the differential diagnosis of a patient presenting with symmetrical descending flaccid paralysis, since immediate treatment with botulinum antitoxin may improve clinical outcomes.
- Subjects
BOTULISM; INTESTINES; COLON cancer; CANCER patients; CLOSTRIDIUM botulinum; ACUTE flaccid paralysis
- Publication
Revista do Instituto de Medicina Tropical de São Paulo, 2019, Vol 61, p1
- ISSN
0036-4665
- Publication type
Article
- DOI
10.1590/S1678-9946201961049