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- Title
Modified Coumarins. 17. Synthesis and Anticoagulant Activity of 3,4-Cycloannelated Coumarin D-Glycopyranosides.
- Authors
Garazd, Ya. L.; Kornienko, E. M.; Maloshtan, L. N.; Garazd, M. M.; Khilya, V. P.
- Abstract
3,4-Cyclocondensed coumarin O-glycopyranosides containing glucose, galactose, xylose, and arabinose were synthesized by condensation of potassium salts of hydroxycoumarins and acetobromosugars. 7-(β-D-Galactopyranosyloxy)-2,3-dihydrocyclopenta[c]chromen-4-one, 3-(β-D-xylopyranosyloxy)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one, and 3-(α-D-arabinopyranosyloxy)benzo[c]chromen-6-one exhibited distinct anticoagulant activity.
- Subjects
ANTICOAGULANTS; HEMATOLOGIC agents; COUMARINS; BENZOPYRANS; CHEMISTRY
- Publication
Chemistry of Natural Compounds, 2005, Vol 41, Issue 5, p508
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-005-0194-8