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- Title
The Role of Dispersion in Particle Deposition in Human Airways.
- Authors
Sarangapani, Ramesh; Wexler, Anthony S.
- Abstract
Aerosol dispersion and deposition are processes that occur concurrently in human airways. However, dispersion has not been properly accounted for in most deposition models. In this paper we have incorporated the latest understanding of dispersion into a dosimetry model and study the influence of dispersion on particle deposition in the lung. We show that dispersion influences the total deposition of inhaled particles and in particular increases the pulmonary deposition of fine mode particles. We also discuss how dispersion can help elucidate a number of clinical and epidemiologic results associated with particle deposition in the lung.
- Subjects
AEROSOLS; AIRWAY (Anatomy); CHEMICAL vapor deposition; AIR pollution; POLLUTANTS
- Publication
Toxicological Sciences, 2000, Vol 54, Issue 1, p229
- ISSN
1096-6080
- Publication type
Article
- DOI
10.1093/toxsci/54.1.229