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- Title
Microtubule assembly, organization and dynamics in axons and dendrites.
- Authors
Conde, Cecilia; Cáceres, Alfredo
- Abstract
During the past decade enormous advances have been made in our understanding of the basic molecular machinery that is involved in the development of neuronal polarity. Far from being mere structural elements, microtubules are emerging as key determinants of neuronal polarity. Here we review the current understanding of the regulation of microtubule assembly, organization and dynamics in axons and dendrites. These studies provide new insight into microtubules' function in neuronal development and their potential contribution to plasticity.
- Subjects
MICROTUBULES; DENDRITES; AXONS; ORGANELLES; MOLECULAR dynamics; NEUROSCIENCES
- Publication
Nature Reviews Neuroscience, 2009, Vol 10, Issue 5, p319
- ISSN
1471-003X
- Publication type
Article
- DOI
10.1038/nrn2631