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- Title
Interaction of Blood and Bacteria with Slippery Hydrophilic Surfaces.
- Authors
Kantam, Prem; Manivasagam, Vignesh K.; Jammu, Tarun Kumar; Sabino, Roberta Maia; Vallabhuneni, Sravanthi; Kim, Young Jae; Kota, Arun K.; Popat, Ketul C.
- Abstract
Slippery surfaces (i.e., surfaces that display high liquid droplet mobility) are receiving significant attention due to their biofluidic applications. Non‐textured, all‐solid, slippery hydrophilic (SLIC) surfaces are an emerging class of rare and counter‐intuitive surfaces. In this work, the interactions of blood and bacteria with SLIC surfaces are investigated. The SLIC surfaces demonstrate significantly lower platelet and leukocyte adhesion (≈97.2% decrease in surface coverage), and correspondingly low platelet activation, as well as significantly lower bacterial adhesion (≈99.7% decrease in surface coverage of live Escherichia Coli and ≈99.6% decrease in surface coverage of live Staphylococcus Aureus) and proliferation compared to untreated silicon substrates, indicating their potential for practical biomedical applications. The study envisions that the SLIC surfaces will pave the path to improved biomedical devices with favorable blood and bacteria interactions.
- Subjects
HYDROPHILIC surfaces; BACTERIAL adhesion; BLOOD platelet activation; MICROBIAL adhesion; BACTERIA; STAPHYLOCOCCUS aureus
- Publication
Advanced Materials Interfaces, 2024, Vol 11, Issue 1, p1
- ISSN
2196-7350
- Publication type
Article
- DOI
10.1002/admi.202300564