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- Title
Hyperleukocytosis in Acute Myeloid Leukemia: Considerations for Inpatient Diagnosis and Management.
- Authors
Wheatley, Tia T.; Castiglione, Haley Foster; Phong, Kenneth; Yoon, Monica
- Abstract
Hyperleukocytosis, a white blood cell count greater than 100,000/mcl, can be associated with the following three primary oncologic emergencies: leukostasis, disseminated intravascular coagulation, and tumor lysis syndrome. These complications significantly increase a patient’s risk of morbidity and mortality. Therefore, timely evidence-based interventions ensure patient safety. This article provides clinical evidence and guidelines for advanced practice nurses working in hematology-oncology to support diagnostic workup and management of hyperleukocytosis in patients with acute myeloid leukemia. A patient case study demonstrates key concepts.
- Subjects
ONCOLOGY nursing; FLUID therapy; HYDROXYUREA; ALLOPURINOL; TUMOR lysis syndrome; MEDICAL protocols; LEUKAPHERESIS; BLOOD cell count; LEUCOCYTE disorders; EVIDENCE-based nursing; DISEASE complications; SYMPTOMS
- Publication
Clinical Journal of Oncology Nursing, 2023, Vol 27, Issue 6, p589
- ISSN
1092-1095
- Publication type
Article
- DOI
10.1188/23.CJON.589-593