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- Title
Polysaccharide-Based Systems for Targeted Stem Cell Differentiation and Bone Regeneration.
- Authors
Witzler, Markus; Büchner, Dominik; Shoushrah, Sarah Hani; Babczyk, Patrick; Baranova, Juliana; Witzleben, Steffen; Tobiasch, Edda; Schulze, Margit
- Abstract
Bone tissue engineering is an ever-changing, rapidly evolving, and highly interdisciplinary field of study, where scientists try to mimic natural bone structure as closely as possible in order to facilitate bone healing. New insights from cell biology, specifically from mesenchymal stem cell differentiation and signaling, lead to new approaches in bone regeneration. Novel scaffold and drug release materials based on polysaccharides gain increasing attention due to their wide availability and good biocompatibility to be used as hydrogels and/or hybrid components for drug release and tissue engineering. This article reviews the current state of the art, recent developments, and future perspectives in polysaccharide-based systems used for bone regeneration.
- Subjects
MESENCHYMAL stem cell differentiation; CELL differentiation; STEM cells; BONE regeneration; BONE cells; CYTOLOGY
- Publication
Biomolecules (2218-273X), 2019, Vol 9, Issue 12, p840
- ISSN
2218-273X
- Publication type
Article
- DOI
10.3390/biom9120840