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- Title
Deconstructing synthetic biology across scales: a conceptual approach for training synthetic biologists.
- Authors
Karim, Ashty S.; Brown, Dylan M.; Archuleta, Chloé M.; Grannan, Sharisse; Aristilde, Ludmilla; Goyal, Yogesh; Leonard, Josh N.; Mangan, Niall M.; Prindle, Arthur; Rocklin, Gabriel J.; Tyo, Keith J.; Zoloth, Laurie; Jewett, Michael C.; Calkins, Susanna; Kamat, Neha P.; Tullman-Ercek, Danielle; Lucks, Julius B.
- Abstract
Synthetic biology allows us to reuse, repurpose, and reconfigure biological systems to address society's most pressing challenges. Developing biotechnologies in this way requires integrating concepts across disciplines, posing challenges to educating students with diverse expertise. We created a framework for synthetic biology training that deconstructs biotechnologies across scales—molecular, circuit/network, cell/cell-free systems, biological communities, and societal—giving students a holistic toolkit to integrate cross-disciplinary concepts towards responsible innovation of successful biotechnologies. We present this framework, lessons learned, and inclusive teaching materials to allow its adaption to train the next generation of synthetic biologists. Developing biotechnologies to address society's challenges requires integrating concepts across disciplines, posing challenges to educating students with diverse expertise. In this Perspective the authors create a framework for synthetic biology training that deconstructs biotechnologies across spatial scales.
- Subjects
SYNTHETIC biology; BIOLOGISTS; BIOTIC communities; BIOLOGICAL systems; TEACHING aids; BIOTECHNOLOGY
- Publication
Nature Communications, 2024, Vol 15, Issue 1, p1
- ISSN
2041-1723
- Publication type
Article
- DOI
10.1038/s41467-024-49626-x