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- Title
PHYTOCHEMICAL SCREENING, ANTIOXIDANT ACTIVITY AND GC-MS ANALYSIS OF CAYRATIA PEDATA (LAM.) GAGNEP. FRUIT.
- Authors
A., Vadivalagan; R., Kannan; S., Vishnu Kumar; G., Divya Bharathi
- Abstract
In the present study, qualitative phytochemical screening and evaluation of antioxidant activity of various solvent extracts of Cayratia pedata fruit were analyzed. The powdered fruit samples were subjected for the extraction by using different solvents such as petroleum ether, chloroform, ethyl acetate, methanol and hot water. The extracts were subjected to quantification of total phenolics, tannin and flavonoids. The in vitro antioxidant assay such as DPPH, ABTS, FRAP, superoxide radical scavenging assay, phosphomolybdenum, Reducing power assay and GC-MS analysis were done. Among the different extracts of C. pedata fruit were studied, the ethyl acetate extract of C. pedata fruit depicted the maximum amount of phenolics (312.82 mg GAE/g extract), tannin (298.01 mg GAE/g extract) and flavonoids (222.03 mg RE/g extract). Highest percentage of DPPH (IC50: 14.47 µg/mL), ABTS (56631.94 µM TE/g extract), FRAP (822.6 mM Fe (II)/mg extract), Superoxide (68.72%) and phosphomolybdenum radical scavenging activity (86.6 mg AAE/g extract) were recorded in the ethyl acetate extract of C. pedata fruit. GC-MS analysis confirmed the presence of different phytochemicals in each fruit extracts of C. pedata of which 10 major phytoconstituents were identified. The present study provides evidence that ethyl acetate extract of C. pedata fruit possesses excellent in vitro antioxidant activity, which can be a potential source of natural antioxidants, should be further exploited for its use in clinical medicine.
- Subjects
PHYTOCHEMICALS; ANTIOXIDANTS; VITACEAE
- Publication
Journal of Advanced Scientific Research, 2020, Vol 11, p174
- ISSN
0976-9595
- Publication type
Article