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- Title
NANO-GOLD PARTICLES MEDIATED DETECTION OF NS1; AN EARLY DIAGNOSTIC MARKER OF DENGUE VIRUS INFECTION.
- Authors
Hussain, A.; Rehman, S. U.; Aslam, S.; Javed, N.; Abbas, Z.
- Abstract
In this study, an immunoassay is developed for qualitative determination of NS1 antigen of dengue virus in serum using nano-gold particles. This diagnostic device comprises of four components such as sample pad, conjugation pad, nitrocellulose membrane and absorbent pad. Anti-NSl antibodies and rabbit anti-mouse IgG antibodies were coated on nitrocellulose membrane as a test and control line respectively. Assay device was evaluated by purified NS1 and prior ELISA confirmed NS1 positive and negative samples. The diagnostic device showed promising results to detect NS1.
- Subjects
DIAGNOSIS of fever; DENGUE; DENGUE viruses; PHYSIOLOGICAL effects of nanoparticles; IMMUNOGLOBULINS; BACTERIAL conjugation
- Publication
JAPS: Journal of Animal & Plant Sciences, 2014, Vol 24, Issue 4, p1110
- ISSN
1018-7081
- Publication type
Article