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- Title
Ultrasound microbubbles combined with liposome-mediated pNogo-R shRNA delivery into neural stem cells.
- Authors
Weixia Ye; Xueping Huang; Yangyang Sun; Hao Liu; Jin Jiang; Youde Cao
- Abstract
The article discusses a study on the feasibility of decreasing Nogo-R protein expression in the ultrasound-mediated microbubble destruction (UMMD) combined with liposome (Lips). The study showed that transfection efficiency of neuro stem cells (NSC) was higher in the group transfected with UMMD combined with Lips compared with that of the group transfected with UMMD or Lips alone. The UMMD with Lips method showed minimal effects on cell viability and increased transfer of Nogo-R shRNA into NSC.
- Subjects
NOGO protein; STEM cells; NOGO receptors; FEASIBILITY studies; GENE transfection; LIPOSOMES
- Publication
Neural Regeneration Research, 2012, Vol 7, Issue 1, p54
- ISSN
1673-5374
- Publication type
Article
- DOI
10.3969/j.issn.1673-5374.2012.01.009