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- Title
Executive Summary: State-of-the-Art Review: Unintended Consequences: Risk of Opportunistic Infections Associated with Long-term Glucocorticoid Therapies in Adults.
- Authors
Chastain, Daniel B; Spradlin, Megan; Ahmad, Hiba; Henao-Martínez, Andrés F
- Abstract
The article focuses on the risks of opportunistic infections (OIs) associated with long-term glucocorticoid therapies in adults, examining factors influencing infection risk and proposing preventive strategies. Topics include the impact of glucocorticoids on immunity; challenges in quantifying infection risk; and strategies for preventing OIs through screening, prophylaxis and immunizations, applicable to various patient populations receiving glucocorticoids.
- Subjects
DRUG therapy for rheumatism; RISK assessment; OPPORTUNISTIC infections; PATIENT safety; APOPTOSIS; LYMPHOCYTES; IMMUNE checkpoint inhibitors; PNEUMOCYSTIS pneumonia; INFLAMMATION; ANTIBIOTIC prophylaxis; GLUCOCORTICOIDS; IMMUNOSUPPRESSION; IMMUNOLOGIC diseases; DISEASE risk factors; ADULTS
- Publication
Clinical Infectious Diseases, 2024, Vol 78, Issue 4, p811
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciae129