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- Title
Burden of rotavirus diarrhea in under-five Indian children.
- Authors
Kumar, Ashok; Basu, Sriparna; Vashishtha, Vipin; Choudhury, Panna
- Abstract
Need and purpose: Rotavirus is the most common cause of severe diarrhea in infants and young children worldwide. The burden of rotavirus diarrhea in Indian children is not well established. The present study reviewed the epidemiology of rotavirus diarrhea in hospitalized children and in the community, molecular serotyping and under-five mortality caused by rotavirus diarrhea. Methods: Publications, reporting rotavirus diarrhea in Indian children, were retrieved through a systematic search of databases including Medline, PubMed, IndMed, websites of WHO, UNICEF, National Family Health Survey, Ministry of Health and Family Welfare, and Government of India. 'Human' studies in 'English' language were included. Age group selected was 0 month to 5 years. No restrictions were applied in terms of study design and time frame. Conclusions: Stool sample positivity varied from 4.6% in Kolkata to 89.8% in Manipur, among hospitalized children, and from 4% in Delhi to 33.7% in Manipur in community. Most cases of rotavirus diarrhea in India are caused by G1, G2, and G untypeable strains with distinct regional variations. Rotavirus was identified as an etiological agent in 5.2 to 80.5% cases of nosocomial diarrhea. Data are lacking for rotavirus mortality.
- Subjects
ROTAVIRUS diseases; DIARRHEA in infants; DIARRHEA in children; HOSPITAL care of children; NOSOCOMIAL infections; SEROTYPING; DISEASE risk factors
- Publication
Indian Pediatrics, 2016, Vol 53, Issue 7, p607
- ISSN
0019-6061
- Publication type
Article
- DOI
10.1007/s13312-016-0896-y