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- Title
Visualization of macromolecular structures.
- Authors
O'Donoghue, Seán I.; Goodsell, David S.; Frangakis, Achilleas S.; Jossinet, Fabrice; Laskowski, Roman A.; Nilges, Michael; Saibil, Helen R.; Schafferhans, Andrea; Wade, Rebecca C.; Westhof, Eric; Olson, Arthur J.
- Abstract
Structural biology is rapidly accumulating a wealth of detailed information about protein function, binding sites, RNA, large assemblies and molecular motions. These data are increasingly of interest to a broader community of life scientists, not just structural experts. Visualization is a primary means for accessing and using these data, yet visualization is also a stumbling block that prevents many life scientists from benefiting from three-dimensional structural data. In this review, we focus on key biological questions where visualizing three-dimensional structures can provide insight and describe available methods and tools.
- Subjects
VISUALIZATION; LIFE sciences; RNA; LIFE scientists; BIOINFORMATICS
- Publication
Nature Methods, 2010, Vol 7, Issue 3s, pS42
- ISSN
1548-7091
- Publication type
Article
- DOI
10.1038/nmeth.1427