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- Title
Cover Feature: A Nickel(II)‐Mediated Thiocarbonylation Strategy for Carbon Isotope Labeling of Aliphatic Carboxamides (Chem. Eur. J. 24/2021).
- Authors
Pedersen, Simon S.; Donslund, Aske S.; Mikkelsen, Jesper H.; Bakholm, Oskar S.; Papp, Florian; Jensen, Kim B.; Gustafsson, Magnus B. F.; Skrydstrup, Troels
- Abstract
Keywords: aliphatic carboxamides; aminocarbonylation; isotope labeling; nickel; thioesters EN aliphatic carboxamides aminocarbonylation isotope labeling nickel thioesters 6998 6998 1 04/30/21 20210426 NES 210426 B Like a rocket b : An extremely fast nickel-mediated thiocarbonylation reaction yielding 2-pyridyl thioesters provides for a convenient carbon-13 labeling approach to the preparation of structurally elaborate aliphatic carboxamides, including both small molecule and peptide APIs. Aliphatic carboxamides, aminocarbonylation, isotope labeling, nickel, thioesters Cover Feature: A Nickel(II)-Mediated Thiocarbonylation Strategy for Carbon Isotope Labeling of Aliphatic Carboxamides (Chem. Eur. J. 24/2021).
- Subjects
RADIOLABELING; CARBON isotopes; CARBOXAMIDES; NICKEL; NICKEL isotopes
- Publication
Chemistry - A European Journal, 2021, Vol 27, Issue 24, p6998
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.202100497