We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Rh-Catalyzed Direct Amination of Unactivated C(sp<sup>3</sup>)−H bond with Anthranils Under Mild Conditions.
- Authors
Tang, Conghui; Zou, MianchENg; Liu, Jianzhong; WEN, Xiaojin; Sun, Xiang; Zhang, Yiqun; Jiao, Ning
- Abstract
C−N Bond formation is of great significance due to the ubiquity of nitrogen-containing compounds. Here, a mild and efficient RhIII-catalyzed C(sp3)−H aryl amination reaction is reported. Anthranil is employed as the nitrogen source with 100 % atom efficiency. This C−H amination reaction exhibits broad substrate scope without using any external oxidants. Mechanistic studies including rhodacycle intermediates, H-D exchange, kinetic isotope effect (KIE) experiments, and in situ IR are presented.
- Subjects
BOND formation mechanism; UBIQUITINATION; AMINATION; KINETIC isotope effects; ISOTOPES
- Publication
Chemistry - A European Journal, 2016, Vol 22, Issue 32, p11165
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.201602556