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- Title
Novel therapies of diabetic nephropathy.
- Abstract
Diabetic nephropathy is currently the most common cause of end stage renal disease not only in the Western hemisphere but also in the developing nations. While the available therapeutic options remain not very effective, there is a strong ongoing effort to understand the pathogenesis better and develop more useful biomarkers. As the pathogenic mediators and signaling pathways get better defined, the scope of novel pharmaceutical agents to address such mediating factors as therapeutic targets is advancing. This review provides, in addition to a brief synopsis of currently used strategies, a comprehensive review of potential therapies that have been evolving in the past decade with a specific focus on the promising agents.
- Subjects
DIABETIC nephropathies; THERAPEUTICS research; CHRONIC kidney failure; BIOMARKERS; ETIOLOGY of diseases; EXPERIMENTAL pharmacology; ACE inhibitors; DISEASE risk factors
- Publication
Nephrology Reviews, 2011, Vol 3, Issue 1, p23
- ISSN
2035-8261
- Publication type
Article
- DOI
10.4081/nr.2011.e4