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- Title
Antibacterial Activity of Paracetamol, Trimethoprim/sulfamethoxazole, Azithromycin, and Ciprofloxacin.
- Authors
Alnaji, Salwuy Aboubakr; Abdalkrim, Hanan; Almahdi, Almahdi Farj; Abdulaziz, Majduldeen; Elsheikhi, Somia M. Abdalla; Abdulhamid, Alzahra Jadullah; Abobakr, Fatima Abdllah; Rajab, No'wara Faraj
- Abstract
Paracetamol have indirect antibiotic activity and are commonly coadministered with antimicrobial therapy. This study aimed to assess the synergistic effect of Paracetamol to with Azithromycin, Trimethoprim/sulfamethoxazole and Ciprofloxacin against salmonella and Escherichia coli. In this study, Ciprofloxacin, Trimethoprim/sulfamethoxazole and Azithromycin was mixed paracetamol against salmonella and Escherichia coli. The results showed that the interaction between Paracetamol and Azithromycin, Trimethoprim/sulfamethoxazole and ciprofloxacin exhibited more in inhibitory potency against on Gram-negative salmonella and Escherichia coli. The combinations of Paracetamol with the Azithromycin and Trimethoprim/sulfamethoxazole showed significant inhibitory activity on the salmonella and Escherichia coli comparing to the inhibition activity showed from the tested antibiotics alone.
- Subjects
ANTIBACTERIAL agents; AZITHROMYCIN; SULFAMETHOXAZOLE; TRIMETHOPRIM; CIPROFLOXACIN; ACETAMINOPHEN; GRAM-negative bacteria
- Publication
Journal of Advanced Zoology, 2023, Vol 44, p396
- ISSN
0253-7214
- Publication type
Article
- DOI
10.17762/jaz.v44is6.2162