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- Title
Effects and Limitations of Naldemedine for Opioid-Induced Urinary Retention: A Case Report.
- Authors
Suzuki, Naoki; Okuyama, Megumi; Kamiya, Kohei
- Abstract
A 78-year-old man with postoperative recurrence of esophageal cancer was admitted to the hospital due to chest pain and dyspnea. Oral short-acting opioids provided some relief, but chest pain persisted and worsened, leading to the initiation of a transdermal fentanyl patch. However, the patient developed opioid-induced urinary retention, which was treated with a naldemedine, a medication used for opioid-induced constipation and urinary retention. Opioid switching led to recurrent urinary retention, requiring placement of a urinary catheter. The patient ultimately required continuous deep sedation for refractory symptoms and died several days later.
- Subjects
NARCOTIC antagonists; ANESTHESIA; FENTANYL; TREATMENT effectiveness; DYSPNEA; URINARY catheters; CHEST pain; RETENTION of urine; DEATH
- Publication
Journal of Palliative Medicine, 2023, Vol 26, Issue 11, p1593
- ISSN
1096-6218
- Publication type
Article
- DOI
10.1089/jpm.2023.0269