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Systems biology reveals anatabine to be an NRF2 activator.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1011184
By:
- Messinis, Dimitris E.;
- Poussin, Carine;
- Latino, Diogo A. R. S.;
- Eb-Levadoux, Yvan;
- Dulize, Remi;
- Peric, Dariusz;
- Guedj, Emmanuel;
- Titz, Bjoern;
- Ivanov, Nikolai V.;
- Peitsch, Manuel C.;
- Hoeng, Julia
Publication type:
Article
Proteomics and Lipidomics in Inflammatory Bowel Disease Research: From Mechanistic Insights to Biomarker Identification.
Published in:
International Journal of Molecular Sciences, 2018, v. 19, n. 9, p. 2775, doi. 10.3390/ijms19092775
By:
- Titz, Bjoern;
- Gadaleta, Raffaella M.;
- Lo Sasso, Giuseppe;
- Elamin, Ashraf;
- Ekroos, Kim;
- Ivanov, Nikolai V.;
- Peitsch, Manuel C.;
- Hoeng, Julia
Publication type:
Article
Alterations in Serum Polyunsaturated Fatty Acids and Eicosanoids in Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD).
Published in:
International Journal of Molecular Sciences, 2016, v. 17, n. 9, p. 1583, doi. 10.3390/ijms17091583
By:
- Titz, Bjoern;
- Luettich, Karsta;
- Leroy, Patrice;
- Boue, Stephanie;
- Vuillaume, Gregory;
- Vihervaara, Terhi;
- Ekroos, Kim;
- Martin, Florian;
- Peitsch, Manuel C.;
- Hoeng, Julia
Publication type:
Article
Acclimation strategies of the green alga Chlorella vulgaris to different light regimes revealed by physiological and comparative proteomic analyses.
Published in:
Journal of Experimental Botany, 2023, v. 74, n. 15, p. 4540, doi. 10.1093/jxb/erad170
By:
- Cecchin, Michela;
- Simicevic, Jovan;
- Chaput, Louise;
- Gil, Manuel Hernandez;
- Girolomoni, Laura;
- Cazzaniga, Stefano;
- Remacle, Claire;
- Hoeng, Julia;
- Ivanov, Nikolai V;
- Titz, Bjoern;
- Ballottari, Matteo
Publication type:
Article
BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint.
Published in:
Nature Medicine, 2013, v. 19, n. 8, p. 1014, doi. 10.1038/nm.3247
By:
- Swaminathan, Srividya;
- Huang, Chuanxin;
- Geng, Huimin;
- Chen, Zhengshan;
- Harvey, Richard;
- Kang, Huining;
- Ng, Carina;
- Titz, Björn;
- Hurtz, Christian;
- Sadiyah, Mohammed Firas;
- Nowak, Daniel;
- Thoennissen, Gabriela B;
- Rand, Vikki;
- Graeber, Thomas G;
- Koeffler, H Phillip;
- Carroll, William L;
- Willman, Cheryl L;
- Hall, Andrew G;
- Igarashi, Kazuhiko;
- Melnick, Ari
Publication type:
Article
Combination of pan-RAF and MEK inhibitors in NRAS mutant melanoma.
Published in:
Molecular Cancer, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12943-015-0293-5
By:
- Atefi, Mohammad;
- Bjoern Titz;
- Avramis, Earl;
- Charles Ng;
- Wong, Deborah J. L.;
- Lassen, Amanda;
- Cerniglia, Michael;
- Escuin-Ordinas, Helena;
- Foulad, David;
- Comin-Anduix, Begonya;
- Graeber, Thomas G.;
- Ribas, Antoni
Publication type:
Article
CRAF R391W is a melanoma driver oncogene.
Published in:
Scientific Reports, 2016, p. 27454, doi. 10.1038/srep27454
By:
- Atefi, Mohammad;
- Titz, Bjoern;
- Tsoi, Jennifer;
- Avramis, Earl;
- Le, Allison;
- Ng, Charles;
- Lomova, Anastasia;
- Lassen, Amanda;
- Friedman, Michael;
- Chmielowski, Bartosz;
- Ribas, Antoni;
- Graeber, Thomas G.
Publication type:
Article
Identification of Small Molecules that Disrupt Signaling between ABL and Its Positive Regulator RIN1.
Published in:
PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0121833
By:
- Ting, Pamela Y.;
- Damoiseaux, Robert;
- Titz, Björn;
- Bradley, Kenneth A.;
- Graeber, Thomas G.;
- Fernández-Vega, Virneliz;
- Bannister, Thomas D.;
- Chase, Peter;
- Nair, Reji;
- Scampavia, Louis;
- Hodder, Peter;
- Spicer, Timothy P.;
- Colicelli, John
Publication type:
Article
Phosphoproteomic Analysis of Platelets Activated by Pro-Thrombotic Oxidized Phospholipids and Thrombin.
Published in:
PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0084488
By:
- Zimman, Alejandro;
- Titz, Bjoern;
- Komisopoulou, Evangelia;
- Biswas, Sudipta;
- Graeber, Thomas G.;
- Podrez, Eugene A.
Publication type:
Article
The Binary Protein Interactome of Treponema pallidum - The Syphilis Spirochete.
Published in:
PLoS ONE, 2008, v. 3, n. 5, p. 1, doi. 10.1371/journal.pone.0002292
By:
- Titz, Björn;
- Rajagopala, Seesandra V.;
- Goll, Johannes;
- Häuser, Roman;
- McKevitt, Matthew T.;
- Palzkill, Timothy;
- Uetz, Peter
Publication type:
Article
The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-60175-3
By:
- Lo Sasso, Giuseppe;
- Phillips, Blaine W.;
- Sewer, Alain;
- Battey, James N. D.;
- Kondylis, Athanasios;
- Talikka, Marja;
- Titz, Bjoern;
- Guedj, Emmanuel;
- Peric, Dariusz;
- Bornand, David;
- Dulize, Remi;
- Merg, Celine;
- Corciulo, Maica;
- Ouadi, Sonia;
- Yanuar, Rendy;
- Tung, Ching Keong;
- Ivanov, Nikolai V.;
- Peitsch, Manuel C.;
- Hoeng, Julia
Publication type:
Article
Transcriptional activators in yeast.
Published in:
Nucleic Acids Research, 2006, v. 34, n. 3, p. 955, doi. 10.1093/nar/gkj493
By:
- Titz, Björn;
- Thomas, Sindhu;
- Rajagopala, Seesandra V.;
- Chiba, Tomoko;
- Ito, Takashi;
- Uetz, Peter
Publication type:
Article
Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study.
Published in:
Romanian Journal of Stomatology / Revista Romana de Stomatologie, 2019, v. 65, n. 2, p. 15, doi. 10.1016/j.fct.2016.12.027
By:
- Zanetti, Filippo;
- Titz, Bjoern;
- Sewer, Alain;
- Lo Sasso, Giuseppe;
- Scotti, Elena;
- Schlage, Walter K.;
- Mathis, Carole;
- Leroy, Patrice;
- Majeed, Shoaib;
- Torres, Laura Ortega;
- Keppler, Brian R.;
- Elamin, Ashraf;
- Trivedi, Keyur;
- Guedj, Emmanuel;
- Martin, Florian;
- Frentzel, Stefan;
- Ivanov, Nikolai V.;
- Peitsch, Manuel C.;
- Hoeng, Julia
Publication type:
Article
The protein network of bacterial motility.
Published in:
Molecular Systems Biology, 2007, v. 3, n. 1, p. 128, doi. 10.1038/msb4100166
By:
- Rajagopala, Seesandra V;
- Titz, Björn;
- Goll, Johannes;
- Parrish, Jodi R;
- Wohlbold, Katrin;
- McKevitt, Matthew T;
- Palzkill, Timothy;
- Mori, Hirotada;
- Finley, Russell L;
- Uetz, Peter
Publication type:
Article
Apical Medium Flow Influences the Morphology and Physiology of Human Proximal Tubular Cells in a Microphysiological System.
Published in:
Bioengineering (Basel), 2022, v. 9, n. 10, p. N.PAG, doi. 10.3390/bioengineering9100516
By:
- Specioso, Gabriele;
- Bovard, David;
- Zanetti, Filippo;
- Maranzano, Fabio;
- Merg, Céline;
- Sandoz, Antonin;
- Titz, Bjoern;
- Dalcanale, Federico;
- Hoeng, Julia;
- Renggli, Kasper;
- Suter-Dick, Laura
Publication type:
Article
Evolutionarily Conserved Herpesviral Protein Interaction Networks.
Published in:
PLoS Pathogens, 2009, v. 5, n. 9, p. 1, doi. 10.1371/journal.ppat.1000570
By:
- Fossum, Even;
- Friedel, Caroline C.;
- Rajagopala, Seesandra V.;
- Titz, Björn;
- Baiker, Armin;
- Schmidt, Tina;
- Kraus, Theo;
- Stellberger, Thorsten;
- Rutenberg, Christiane;
- Suthram, Silpa;
- Bandyopadhyay, Sourav;
- Rose, Dietlind;
- von Brunn, Albrecht;
- Uhlmann, Mareike;
- Zeretzke, Christine;
- Yu-An Dong;
- Boulet, Hélène;
- Koegl, Manfred;
- Bailer, Susanne M.;
- Koszinowski, Ulrich
Publication type:
Article
Impact of whole‐body versus nose‐only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2‐month cigarette smoke exposure study in the ApoE−/− mouse model.
Published in:
Journal of Applied Toxicology, 2021, v. 41, n. 10, p. 1598, doi. 10.1002/jat.4149
By:
- Kogel, Ulrike;
- Wong, Ee Tsin;
- Szostak, Justyna;
- Tan, Wei Teck;
- Lucci, Francesco;
- Leroy, Patrice;
- Titz, Bjoern;
- Xiang, Yang;
- Low, Tiffany;
- Wong, Sin Kei;
- Guedj, Emmanuel;
- Ivanov, Nikolai V.;
- Schlage, Walter K.;
- Peitsch, Manuel C.;
- Kuczaj, Arkadiusz;
- Vanscheeuwijck, Patrick;
- Hoeng, Julia
Publication type:
Article
A 6-month inhalation toxicology study in Apoe−/− mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract.
Published in:
Archives of Toxicology, 2021, v. 95, n. 5, p. 1805, doi. 10.1007/s00204-021-03020-4
By:
- Wong, Ee Tsin;
- Szostak, Justyna;
- Titz, Bjoern;
- Lee, Tom;
- Wong, Sin Kei;
- Lavrynenko, Oksana;
- Merg, Celine;
- Corciulo, Maica;
- Simicevic, Jovan;
- Auberson, Mehdi;
- Peric, Dariusz;
- Dulize, Remi;
- Bornand, David;
- Loh, Guo Jie;
- Lee, Kyeonghee Monica;
- Zhang, Jingjie;
- Miller IV, John H.;
- Schlage, Walter K.;
- Guedj, Emmanuel;
- Schneider, Thomas
Publication type:
Article
E-vapor aerosols do not compromise bone integrity relative to cigarette smoke after 6-month inhalation in an ApoE–/– mouse model.
Published in:
Archives of Toxicology, 2020, v. 94, n. 6, p. 2163, doi. 10.1007/s00204-020-02769-4
By:
- Reumann, Marie K.;
- Schaefer, Jenny;
- Titz, Bjoern;
- Aspera-Werz, Romina H.;
- Wong, Ee Tsin;
- Szostak, Justyna;
- Häussling, Victor;
- Ehnert, Sabrina;
- Leroy, Patrice;
- Tan, Wei Teck;
- Kuczaj, Arkadiusz;
- Audretsch, Christof;
- Springer, Fabian;
- Badke, Andreas;
- Augat, Peter;
- Quentanilla-Fend, Leticia;
- Martella, Manuela;
- Lee, K. Monica;
- Peitsch, Manuel C.;
- Hoeng, Julia
Publication type:
Article
Evaluation of toxicity of aerosols from flavored e-liquids in Sprague–Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis.
Published in:
Archives of Toxicology, 2020, v. 94, n. 6, p. 2179, doi. 10.1007/s00204-020-02759-6
By:
- Ho, Jenny;
- Sciuscio, Davide;
- Kogel, Ulrike;
- Titz, Bjoern;
- Leroy, Patrice;
- Vuillaume, Gregory;
- Talikka, Marja;
- Martin, Elyette;
- Pospisil, Pavel;
- Lebrun, Stefan;
- Xia, Wenhao;
- Lee, Tom;
- Chng, Yun Xuan;
- Phillips, Blaine W.;
- Veljkovic, Emilija;
- Guedj, Emmanuel;
- Xiang, Yang;
- Ivanov, Nikolai V.;
- Peitsch, Manuel C.;
- Hoeng, Julia
Publication type:
Article
Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.
Published in:
Nature, 2015, v. 521, n. 7552, p. 357, doi. 10.1038/nature14231
By:
- Chen, Zhengshan;
- Shojaee, Seyedmehdi;
- Buchner, Maike;
- Geng, Huimin;
- Lee, Jae Woong;
- Klemm, Lars;
- Titz, Björn;
- Graeber, Thomas G.;
- Park, Eugene;
- Tan, Ying Xim;
- Satterthwaite, Anne;
- Paietta, Elisabeth;
- Hunger, Stephen P.;
- Willman, Cheryl L.;
- Melnick, Ari;
- Loh, Mignon L.;
- Jung, Jae U.;
- Coligan, John E.;
- Bolland, Silvia;
- Mak, Tak W.
Publication type:
Article
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E).
Published in:
Nature, 2011, v. 480, n. 7377, p. 387, doi. 10.1038/nature10662
By:
- Poulikakos, Poulikos I.;
- Persaud, Yogindra;
- Janakiraman, Manickam;
- Kong, Xiangju;
- Ng, Charles;
- Moriceau, Gatien;
- Shi, Hubing;
- Atefi, Mohammad;
- Titz, Bjoern;
- Gabay, May Tal;
- Salton, Maayan;
- Dahlman, Kimberly B.;
- Tadi, Madhavi;
- Wargo, Jennifer A.;
- Flaherty, Keith T.;
- Kelley, Mark C.;
- Misteli, Tom;
- Chapman, Paul B.;
- Sosman, Jeffrey A.;
- Graeber, Thomas G.
Publication type:
Article
RsfA (YbeB) Proteins Are Conserved Ribosomal Silencing Factors.
Published in:
PLoS Genetics, 2012, v. 8, n. 7, p. 1, doi. 10.1371/journal.pgen.1002815
By:
- Häuser, Roman;
- Pech, Markus;
- Kijek, Jaroslaw;
- Yamamoto, Hiroshi;
- Titz, Björn;
- Naeve, Florian;
- Tovchigrechko, Andrey;
- Yamamoto, Kaori;
- Szaflarski, Witold;
- Takeuchi, Nono;
- Stellberger, Thorsten;
- Diefenbacher, Markus E.;
- Nierhaus, Knud H.;
- Uetz, Peter
Publication type:
Article
Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice.
Published in:
Toxicological Sciences, 2020, v. 178, n. 1, p. 138, doi. 10.1093/toxsci/kfaa132
By:
- Titz, Bjoern;
- Sewer, Alain;
- Luettich, Karsta;
- Wong, Ee Tsin;
- Guedj, Emmanuel;
- Nury, Catherine;
- Schneider, Thomas;
- Xiang, Yang;
- Trivedi, Keyur;
- Vuillaume, Grégory;
- Leroy, Patrice;
- Büttner, Ansgar;
- Martin, Florian;
- Ivanov, Nikolai V;
- Vanscheeuwijck, Patrick;
- Hoeng, Julia;
- Peitsch, Manuel C
Publication type:
Article
Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe-/- Mice-An Integrative Systems Toxicology Analysis.
Published in:
Toxicological Sciences, 2016, v. 149, n. 2, p. 441, doi. 10.1093/toxsci/kfv244
By:
- Titz, Bjoern;
- Boué, Stéphanie;
- Phillips, Blaine;
- Talikka, Marja;
- Vihervaara, Terhi;
- Schneider, Thomas;
- Nury, Catherine;
- Elamin, Ashraf;
- Guedj, Emmanuel;
- Peck, Michael J.;
- Schlage, Walter K.;
- Cabanski, Maciej;
- Leroy, Patrice;
- Vuillaume, Gregory;
- Martin, Florian;
- Martin, Nikolai V.;
- Veljkovic, Emilija;
- Kim Ekroos;
- Laaksonen, Reijo;
- Vanscheeuwijck, Patrick
Publication type:
Article
An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.
Published in:
Toxicological Sciences, 2016, v. 149, n. 2, p. 411, doi. 10.1093/toxsci/kfv243
By:
- Phillips, Blaine;
- Veljkovic, Emilija;
- Boué, Stéphanie;
- Schlage, Walter K.;
- Vuillaume, Gregory;
- Martin, Florian;
- Titz, Bjoern;
- Leroy, Patrice;
- Buettner, Ansgar;
- Elamin, Ashraf;
- Oviedo, Alberto;
- Cabanski, Maciej;
- León, Héctor De;
- Guedj, Emmanuel;
- Schneider, Thomas;
- Talikka, Marja;
- Ivanov, Nikolai V.;
- Vanscheeuwijck, Patrick;
- Peitsch, Manuel C.;
- Julia Hoeng
Publication type:
Article
MPI-LIT: a literature-curated dataset of microbial binary protein--protein interactions.
Published in:
Bioinformatics, 2008, v. 24, n. 22, p. 2622, doi. 10.1093/bioinformatics/btn481
By:
- Seesandra V. Rajagopala;
- Johannes Goll;
- N.D. Deve Gowda;
- Kumar C. Sunil;
- Björn Titz;
- Arnab Mukherjee;
- Sharmila S. Mary;
- Naresh Raviswaran;
- Chetan S. Poojari;
- Srinivas Ramachandra;
- Svetlana Shtivelband;
- Stephen M. Blazie;
- Julia Hofmann;
- Peter Uetz
Publication type:
Article
Blood and urine multi-omics analysis of the impact of e-vaping, smoking, and cessation: from exposome to molecular responses.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-54474-2
By:
- Poussin, Carine;
- Titz, Bjoern;
- Xiang, Yang;
- Baglia, Laurel;
- Berg, Rachel;
- Bornand, David;
- Choukrallah, Mohammed-Amin;
- Curran, Timothy;
- Dijon, Sophie;
- Dossin, Eric;
- Dulize, Remi;
- Etter, Doris;
- Fatarova, Maria;
- Medlin, Loyse Felber;
- Haiduc, Adrian;
- Kishazi, Edina;
- Kolli, Aditya R.;
- Kondylis, Athanasios;
- Kottelat, Emmanuel;
- Laszlo, Csaba
Publication type:
Article
Global Phosphoproteomics Reveals Crosstalk Between Bcr-Abl and Negative Feedback Mechanisms Controlling Src Signaling.
Published in:
Science Signaling, 2011, v. 4, n. 166, p. 1, doi. 10.1126/scisignal.2001314
By:
- Rubbi, Liudmilla;
- Titz, Björn;
- Brown, Lauren;
- Galvan, Erica;
- Komisopoulou, Evangelia;
- Chen, Sharon S.;
- Low, Tracey;
- Tahmasian, Martik;
- Skaggs, Brian;
- Müschen, Markus;
- Pellegrini, Matteo;
- Graeber, Thomas G.
Publication type:
Article

Found: 29

Systems biology reveals anatabine to be an NRF2 activator.

Proteomics and Lipidomics in Inflammatory Bowel Disease Research: From Mechanistic Insights to Biomarker Identification.

Alterations in Serum Polyunsaturated Fatty Acids and Eicosanoids in Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD).

Acclimation strategies of the green alga Chlorella vulgaris to different light regimes revealed by physiological and comparative proteomic analyses.

BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint.

Combination of pan-RAF and MEK inhibitors in NRAS mutant melanoma.

CRAF R391W is a melanoma driver oncogene.

Identification of Small Molecules that Disrupt Signaling between ABL and Its Positive Regulator RIN1.

Phosphoproteomic Analysis of Platelets Activated by Pro-Thrombotic Oxidized Phospholipids and Thrombin.

The Binary Protein Interactome of Treponema pallidum - The Syphilis Spirochete.

The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts.

Transcriptional activators in yeast.

Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study.

The protein network of bacterial motility.

Apical Medium Flow Influences the Morphology and Physiology of Human Proximal Tubular Cells in a Microphysiological System.

Evolutionarily Conserved Herpesviral Protein Interaction Networks.

Impact of whole‐body versus nose‐only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2‐month cigarette smoke exposure study in the ApoE<sup>−/−</sup> mouse model.

A 6-month inhalation toxicology study in Apoe−/− mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract.

E-vapor aerosols do not compromise bone integrity relative to cigarette smoke after 6-month inhalation in an ApoE–/– mouse model.

Evaluation of toxicity of aerosols from flavored e-liquids in Sprague–Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis.

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.

RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E).

RsfA (YbeB) Proteins Are Conserved Ribosomal Silencing Factors.

Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice.

Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe<sup>-/-</sup> Mice-An Integrative Systems Toxicology Analysis.

An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe<sup>-/-</sup> Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.

MPI-LIT: a literature-curated dataset of microbial binary protein--protein interactions.

Blood and urine multi-omics analysis of the impact of e-vaping, smoking, and cessation: from exposome to molecular responses.

Global Phosphoproteomics Reveals Crosstalk Between Bcr-Abl and Negative Feedback Mechanisms Controlling Src Signaling.