We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Discovering Genomic Regions Associated with Reproductive Traits and Frame Score in Mexican Simmental and Simbrah Cattle Using Individual SNP and Haplotype Markers.
- Authors
Calderón-Chagoya, René; Vega-Murillo, Vicente Eliezer; García-Ruiz, Adriana; Ríos-Utrera, Ángel; Martínez-Velázquez, Guillermo; Montaño-Bermúdez, Moisés
- Abstract
Reproductive efficiency stands as a critical determinant of profitability within beef production systems. The incorporation of molecular markers can expedite advancements in reproductive performance. While the use of SNPs in association analysis is prevalent, approaches centered on haplotypes can offer a more comprehensive insight. The study used registered Simmental and Simbrah cattle genotyped with the GGP Bovine 150 k panel. Phenotypes included scrotal circumference (SC), heifer fertility (HF), stayability (STAY), and frame score (FS). After quality control, 105,129 autosomal SNPs from 967 animals were used. Haplotype blocks were defined based on linkage disequilibrium. Comparison between haplotypes and SNPs for reproductive traits and FS was conducted using Bayesian and frequentist models. 23, 13, 7, and 2 SNPs exhibited associations with FS, SC, HF, and STAY, respectively. In addition, seven, eight, seven, and one haplotypes displayed associations with FS, SC, HF, and STAY, respectively. Within these delineated genomic segments, potential candidate genes were associated.
- Subjects
HAPLOTYPES; SIMMENTAL cattle; CATTLE genetics; SINGLE nucleotide polymorphisms; LINKAGE disequilibrium; BEEF industry; RANCHING
- Publication
Genes, 2023, Vol 14, Issue 11, p2004
- ISSN
2073-4425
- Publication type
Article
- DOI
10.3390/genes14112004