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- Title
The History of Enterovirus A71 Outbreaks and Molecular Epidemiology in the Asia-Pacific Region.
- Authors
Jiratchaya Puenpa; Nasamon Wanlapakorn; Sompong Vongpunsawad; Yong Poovorawan
- Abstract
Enterovirus A71 (EV-A71) is one of the common causative pathogens for hand foot and mouth disease (HFMD)affecting young children. HFMD outbreak can result in a substantial pediatric hospitalization and burden thehealthcare services, especially in less-developed countries. Since the initial epidemic of predominantly EV-A71 inCalifornia in 1969, the high prevalence of HFMD in the Asia-pacific region and elsewhere around the worldrepresents a significant morbidity in this age group. With the advent of rapid and accurate diagnostic tools, therehas been a dramatic increase in the number of laboratory-confirmed EV-A71 infection over the past two decades.The population, cultural, and socioeconomic diversity among countries in the Asia-Pacific region all influence thetransmission and morbidity associated with HFMD. This review summarizes the current state of epidemiology of EV-A71in Asia-Pacific countries based on the most recent epidemiological data and available information on the prevalence anddisease burden. This knowledge is important in guiding the prevention, control and future research on vaccinedevelopment of this highly contagious disease of significant socioeconomic implications in public health.
- Publication
Journal of Biomedical Science, 2019, Vol 26, Issue 1, p1
- ISSN
1021-7770
- Publication type
Article
- DOI
10.1186/s12929-019-0573-2