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- Title
Loop Duodenojejunal Bypass with Sleeve Gastrectomy: Comparative Study with Roux-en-Y Gastric Bypass in Type 2 Diabetic Patients with a BMI <35 kg/m, First Year Results.
- Authors
Huang, Chih; Tai, Chi-Ming; Chang, Po-Chih; Malapan, Kirubakaran; Tsai, Ching-Chung; Yolsuriyanwong, Kamthorn
- Abstract
Background: Roux-en-Y gastric bypass (RYGB) has shown good diabetes remission in obese patients with type 2 diabetes mellitus (T2DM), but long-term complications were observed. We developed loop duodenojejunal bypass with sleeve gastrectomy (LDJB-SG) to achieve diabetes remission and avoid the drawbacks of RYGB. We compare 1-year results between LDJB-SG and RYGB with body mass index (BMI) <35 kg/m of T2DM patients. Methods: We conducted a case-matched study of BMI < 35 kg/m T2DM patients who underwent RYGB and LDJB-SG matching on age, BMI, and duration of diabetes. The 1-year surgical results were compared. Results: Sixty patients were included from March 2010 to August 2012. Thirty patients underwent RYGB and 30 underwent LDJB-SG. The operative time (mean ± SD) and length of stay (median [IQR]) were significantly longer in the LDJB-SG group than in the RYGB group (127.0 ± 40.2 vs. 105.0 ± 64.7 min and 3[3, 4] vs. 3[2, 3] days, respectively). There were no statistical differences between the groups in the mean BMI, fasting plasma glucose, and %HbA1c either at baseline or at 1 year. However, these parameters dropped significantly from the preoperative values ( p < 0.01). The level of HOMA-%B at 1 year was significantly higher in the LDJB-SG group than in the RYGB group ( p = 0.004). The resolution of comorbidities was similar. Late complications seemed higher in the RYGB group (12 vs. 5, p = 0.08). There were no deaths, but two patients in each group required reoperation. Conclusions: LDJB-SG was comparable to RYGB in terms of weight loss, glycemic control, and comorbidity resolution in BMI <35 kg/m T2DM patients in the short-term.
- Subjects
JEJUNOILEAL bypass; GASTRECTOMY; COMPARATIVE studies; PEOPLE with diabetes; BODY mass index; DISEASE remission
- Publication
Obesity Surgery, 2016, Vol 26, Issue 10, p2291
- ISSN
0960-8923
- Publication type
Article
- DOI
10.1007/s11695-016-2118-z