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- Title
The Impact of Bariatric Surgery on Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis.
- Authors
Skubleny, Daniel; Switzer, Noah; Gill, Richdeep; Dykstra, Mark; Shi, Xinzhe; Sagle, Margaret; Gara, Christopher; Birch, Daniel; Karmali, Shahzeer
- Abstract
Bariatric surgery has been proven to be a successful management strategy for morbid obesity, but limited studies exist on its effect on polycystic ovary syndrome (PCOS). A comprehensive search of electronic databases was completed. Meta-analysis was performed on PCOS, hirsutism, and menstrual irregularity outcomes following bariatric surgery. Thirteen primary studies involving a total of 2130 female patients were identified. The incidence of PCOS preoperatively was 45.6 %, which significantly decreased to 6.8 % ( P < 0.001) and 7.1 % ( P < 0.0002) at 12-month follow-up and study endpoint, respectively. The incidences of preoperative menstrual irregularity and hirsutism both significantly decreased at 12-month and at study end follow-up. Bariatric surgery effectively attenuates PCOS and its clinical symptomatology including hirsutism and menstrual irregularity in severely obese women.
- Subjects
POLYCYSTIC ovary syndrome; BARIATRIC surgery; SYSTEMATIC reviews; HYPERTRICHOSIS; MENSTRUATION disorders
- Publication
Obesity Surgery, 2016, Vol 26, Issue 1, p169
- ISSN
0960-8923
- Publication type
Article
- DOI
10.1007/s11695-015-1902-5