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- Title
Solitary fibrous tumor of the kidney: a report of two cases.
- Authors
Oliveira, Rui Pedro Caetano M.; Silva, Edgar Miguel C. L. T.; dos Anjos Marinho, Carol; Ignacio Lopez, José; Castro, Lígia Romana O. A. P.
- Abstract
Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, composed of monotonous spindle cells, intermingled with collagen fibers. Kidney location is sporadic, with few reports in literature. We present two cases of 40- and 48-year-old males, one with incidental detection of a peripheral mass; another with hilar lesion perceived following investigation of hematuria. Both revealed a spindle-cell proliferation, without mitosis and necrosis. Immunohistochemical studies: positivity for CD34, CD99 and B-cell lymphoma 2 (Bcl-2). No sign of disease were evident nine and five months after surgery, respectively. SFT is mostly benign, but can show malignant behavior. Morphologic and immunohistochemical characteristics are essential for diagnosis.
- Subjects
MESENCHYMAL stem cells; HEMATURIA; SURGERY; IMMUNOHISTOCHEMISTRY; RENAL cancer
- Publication
Jornal Brasileiro de Patologia e Medicina Laboratorial, 2019, Vol 55, Issue 1, p118
- ISSN
1676-2444
- Publication type
Article
- DOI
10.5935/1676-2444.20190003