We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Tolerance to Effects of High-Dose Oral Δ9-Tetrahydrocannabinol and Plasma Cannabinoid Concentrations in Male Daily Cannabis Smokers.
- Authors
Gorelick, David A.; Goodwin, Robert S.; Schwilke, Eugene; Schwope, David M.; Darwin, William D.; Kelly, Deanna L.; McMahon, Robert P.; Liu, Fang; Ortemann-Renon, Catherine; Bonnet, Denis; Huestis, Marilyn A.
- Abstract
The article focuses on a study that evaluates tolerance to effects of high dose oral tetrahydrocannabinol (THC) and plasma cannabinoids in male cannabis smokers. It mentions that systolic and diastolic blood pressure (BP), heart rate and symptoms of subjective intoxication were assessed in 13 healthy male daily cannabis smokers. The results indicated that THC lowered BP and increased heart rate and also produces tolerance to subjective intoxication, but not to cardiovascular effects.
- Subjects
TETRAHYDROCANNABINOL; CANNABINOIDS; HALLUCINOGENIC drugs; CARDIOTOXICITY; BLOOD pressure measurement; HEART rate monitoring; CARDIOVASCULAR agents
- Publication
Journal of Analytical Toxicology, 2013, Vol 37, Issue 1, p11
- ISSN
0146-4760
- Publication type
Article
- DOI
10.1093/jat/bks081