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- Title
Adhesion Molecules, Stem Cells, and the Microenvironment in Acute Myeloid Leukemia.
- Authors
Brower, Vicki
- Abstract
The article focuses on the microenvironment in acute myeloid leukemia as well as adhesion molecules and stem cells. It provides details about a trial entitled "Homing of leukemia cells to the bone marrow depends on CXCR4, a chemokine receptor, which the drug BL-8040 blocked." Other information related to the disruption of cancer cell adhesion to the bone marrow is presented.
- Subjects
ACUTE myeloid leukemia; CELL adhesion molecules; STEM cells; CANCER cells; BONE marrow; CELL adhesion; CHEMOKINES; ANTINEOPLASTIC agents; CELL physiology; CELL receptors; DRUG resistance in cancer cells; HETEROCYCLIC compounds; SULFONAMIDES; PHARMACODYNAMICS
- Publication
JNCI: Journal of the National Cancer Institute, 2016, Vol 108, Issue 4, p3
- ISSN
0027-8874
- Publication type
journal article
- DOI
10.1093/jnci/djw113