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- Title
Anemia is Associated With Mortality Following Endovascular Repair of Abdominal Aortic Aneurysm.
- Authors
Saratzis, Athanasios; Melas, Nikolaos; Hunter, James P.; Dixon, Hannah; Nightingale, Peter; Kiskinis, Dimitrios; Saratzis, Nikolaos; Kitas, George D.
- Abstract
Aim: The aim of this study was to compare midterm mortality between anemic and nonanemic patients undergoing endovascular repair of abdominal aortic aneurysm and to assess a correlation with markers of inflammation. Methods: Anemia was defined as hemoglobin <13 (men) and <12 g/dL (women). The impact of anemia and inflammatory markers on mortality was assessed using Kaplan-Meier curves and Cox regression. Results: A total of 224 patients (12 females [5.36%]; age: 69.73 ± 8.72 years) were included; 102 (45.53%) were anemic. Median follow-up was 17 months (interquartile range: 7-25 months). Nine patients died (1.79%; 8 anemic vs 1 nonanemic). Survival was lower for patients with anemia (log-rank, P = .01). White blood cell count and C-reactive protein (CRP) differed significantly (P < .001 and P = .01). Anemia and CRP were associated with decreased survival (Cox regression, P = .01, hazard ratio [HR]: 0.35, 95% confidence interval: 0.14-0.84 and P = .002, HR: 1.18, 95% CI: 1.06-1.31). Conclusion: Patients with anemia had decreased survival over the midterm; inflammatory markers were higher among this group.
- Subjects
MORTALITY risk factors; ABDOMINAL aortic aneurysms; ANEMIA; BIOMARKERS; VASCULAR surgery; CONFIDENCE intervals; CAUSES of death; FISHER exact test; LONGITUDINAL method; SURVIVAL analysis (Biometry); T-test (Statistics); U-statistics; DATA analysis software; DESCRIPTIVE statistics
- Publication
Vascular & Endovascular Surgery, 2012, Vol 46, Issue 3, p223
- ISSN
1538-5744
- Publication type
Article
- DOI
10.1177/1538574412442251