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- Title
Antimicrobial and antifungal activity of model drugs on the basis of food plant extracts in the systemic concept of health.
- Authors
Oseyko, Mykola; Shevchyk, Vasyl; Pokryshko, Olena
- Abstract
Introduction. We analyzed the antimicrobial and antifungal activity of samples of the preparation of KTIOL-BF on standard and resistant test strains of microorganisms. The aspects of microbiology and the systemic concept of health are considered. Materials and methods. Strains of Gram-positive and Gramnegative microorganisms were used: S. aureus, S. saprophyticus, E. coli, P. aeruginosa, S. Epidermidis, and C. albicans fungi. Model drugs based on pyruvic extracts have been studied. The method of diffusion of substances into agar was used to determine the activity of drugs in relation to strains.. Results and discussion. The present state of physical, psychological and social existence of a person contributes to the accelerated proliferation of pathogenic microorganisms and the emergence of a resistant microflora. In recent years, almost everyone suffers from fungal diseases. The problem of health and healthy lifestyle is topical. Global is the problem of providing humanity with food. Considered aspects of microbiome (endoecological aspectsT he importance of intestinal microbiota in human health and pathophysiology is indisputable. Suggested the systemic concept of health (The systems KTIOL®: 10 Basic Provisions for Prevention, Recovery, Treatment and Rehabilitation). The tested microorganisms were sensitive to model specimens of the preparation KTIOL-BF (BF1-BF20). Samples of BF2, BF12, BF17 were found to be the most effective for the S. Saprophyticus test strain. It was found that the S. epidermidis test-microorganism was the most effective for the sample of the preparation BF34 (growth retardation zone was 30.40 ± 1.29 mm). The highest antifungal activity was found in samples of KTIOL-BF: BF33, BF37. Mushroom growth zones were respectively 20.76 ± 1.65 and 22.62 ± 1.44 mm. The samples of the KTIOL-BF: BF-70, BF-87, BF-92 were shown to have a high inhibitory effect on clinical resistant strains of microorganisms. The diameter of the inhibition zone of resistant strains in KTIOL-BF87 was 22.17 mm; the diameter of the PVI control sample was 13.05 mm. Conclusions. The raised antimicrobial and antifungal activity of KTIOL-BF preparations in relation to gram-positive and gramnegative microorganisms, C. albicans fungi and resistant strains (PVI control) were revealed.
- Subjects
ANTIFUNGAL agents; PLANT extracts; FERTILIZERS; PATHOGENIC microorganisms; MYCOSES; HUMAN microbiota
- Publication
Ukrainian Journal of Food Science, 2019, Vol 7, Issue 1, p70
- ISSN
2310-1008
- Publication type
Article
- DOI
10.24263/2310-1008-2019-7-1-9