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- Title
Regioselective Synthesis of Novel Functionalized Pyrano[2′,3′:4,5]pyrimido[1,6-b][1,2,4,5]triazaphosphepines.
- Authors
Ali, T. E.; Assiri, M. A.; Yahia, I. S.; Zahran, H. Y.; Meselhy, M. H.; Hussien, M. S. A.
- Abstract
The reactions of 6-acetyl-3-amino-4-imino-7-methyl-5-phenyl-3,5-dihydro-4H-pyrano[2,3-d]pyrimidine with triethyl phosphite and some electrophilic reagents, namely 1,2-dibromoethane, oxalyl chloride, chloroacetyl chloride, and ethyl chloroacetate, were studied. These one-pot three-component reactions regioselectively afforded four new 11-acetyl-2-ethoxy-10-methyl-12-phenylpyrano[2′,3′:4,5]pyrimido[1,6-b][1,2,4,5λ5]triazaphosphepin-2-ones in 69–73% yields.
- Subjects
ELECTROPHILES; OXALYL chloride
- Publication
Russian Journal of Organic Chemistry, 2021, Vol 57, Issue 1, p79
- ISSN
1070-4280
- Publication type
Article
- DOI
10.1134/S1070428021010115