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- Title
Synthesis and Anticonvulsant Activity of Amino Amides and Amino Esters Based on 1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-cyclopentane-1-carboxylic Acid.
- Authors
Arustamyan, Zh. S.; Markaryan, R. E.; Aghekyan, A. A.; Nazaryan, I. M.; Hakobyan, A. G.; Paronikyan, R. G.; Minasyan, N. S.
- Abstract
Alkaline hydrolysis of 1-(2,3-dihydro-1,4-benzodioxin-6-yl)cyclopentane-1-carbonitrile gave the corresponding carboxylic acid which was converted to carbonyl chloride, and the latter reacted with N, N-di-alkylalkane-α,ω-diamines and dialkylaminoalkanols to afford new amino amides and amino esters which were isolated as hydrochlorides. Anticonvulsant activity of the synthesized compounds was studied.
- Subjects
AMIDES; PHOSGENE; CARBOXYLIC acids; ESTERS; ACIDS; HYDROLYSIS
- Publication
Russian Journal of Organic Chemistry, 2019, Vol 55, Issue 6, p796
- ISSN
1070-4280
- Publication type
Article
- DOI
10.1134/S1070428019060095