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- Title
Cutaneous and ocular adverse reactions in a dog following meloxicam administration.
- Authors
Niza, Maria M. R. E.; Félix, Nuno; Vilela, Cristina L.; Peleteiro, Maria C.; Ferreira, Antonio J. A.
- Abstract
The present report addresses the development of cutaneous and ocular reactions possibly related to meloxicam administration in a dog. Based on clinical signs and absence of laboratory data compatible with the other differential diagnoses considered, the possibility of an adverse drug reaction (ADR) due to meloxicam was considered. Skin biopsy revealed haemorrhage of the superficial and deep dermis, associated with hyperplasia of endothelial cells and epidermal sloughing. Vasculitis in the deep dermis was also noted. Such lesions were considered compatible with an ADR. Although the owner was not aware of any previous allergic reaction to drugs, the animal had a clinical history of atopic dermatitis. Meloxicam is a nonsteroid anti-inflammatory drug (NSAID) in the oxicam family, indicated for the control of inflammation and pain in acute and chronic musculoskeletal disorders in dogs. Although meloxicam is usually well tolerated, the present clinical case represents an alert to practitioners about the potential role of NSAIDS in ADRs in dogs with a history of allergic cutaneous diseases.
- Subjects
SKIN diseases; DRUG side effects; ATOPIC dermatitis; NONSTEROIDAL anti-inflammatory agents; DOGS; VETERINARY medicine
- Publication
Veterinary Dermatology, 2007, Vol 18, Issue 1, p45
- ISSN
0959-4493
- Publication type
Article
- DOI
10.1111/j.1365-3164.2007.00566.x